Tissue Engineering Innovations
Solutions To Global Problems
Macular degeneration is a leading cause of vision loss in Americans 60 years of age and older. As many as 11 million people in the United States have some form of age-related macular degeneration. This number is expected to double to nearly 22 million by 2050. The number of people living with macular degeneration is expected to reach 196 million worldwide by 2020 and increase to 288 million by 2040.
Estimates of the global cost of visual impairment due to age-related macular degeneration is $343 billion, including $255 billion in direct health care costs.
196
Million People
The number of people living with macular degeneration is expected to reach 196 million worldwide by 2020 and increase to 288 million by 2040.
661,000Americans
The number of Americans that have kidney failure. Of these, 468,000 individuals are on dialysis, and roughly 193,000 live with a functioning kidney transplant.
$343Billion
The estimated global cost of visual impairment due to age-related macular degeneration is $343 billion, including $255 billion in direct health care costs.
Macular Degeneration Cure
Macular degeneration remains incurable. Existing therapies slow
decline but do not restore vision.
Mesogen Will Solve This Crisis
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Mesogen will be a provider of autologous engineered Retinal Pigment Epithelium (RPE) cell patches for transplant. This will be a curative treatment.
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These patches can be grown in about 2 months with our proprietary process, and the patient's own cells.
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The patient will not require long-term anti-rejection drugs and will have a better quality of life with less complications.
The Mesogen Diabetes Solution: Personalized Cell Therapy
Diabetes remains a chronic, progressive disease. Current therapies
manage blood glucose but do not restore endogenous insulin production or
reverse beta-cell loss. Long-term disease management often requires lifelong
pharmacologic intervention and ongoing monitoring, with cumulative risk of
complications over time.
The Mesogen Solution
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Autologous approach: Investigating patient-derived insulin-producing beta-like cells for transplant using a proprietary, time-bound process.
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Reduced immunologic burden: Use of a patient’s own cells is designed to avoid the need for long-term anti-rejection therapy.
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Scientific objective: To explore whether regenerative strategies can support more durable metabolic function and improved long-term disease management.
About Mesogen
Mesogen will be a provider of autologous engineered Retinal Pigment Epithelium (RPE) cell patches for transplant. This will be a curative treatment. Headquartered in the Woodlands, Texas, in the United States, the company will focus on solving some of the largest problems facing humanity through advanced tissue engineering innovations.
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Led by Michael Riddle, MD, an accomplished life science technology professional with over 15 years laboratory experience.
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Research projects include retinal tissue, lung, kidney, heart and heart valve regenerative medicine research.
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Successful commercialization and diversification through asset sales